TFDP3 regulates the apoptosis and autophagy in breast cancer cell line MDA-MB-231.
Cancer/testis antigen TFDP3 belongs to the transcription factor DP(TFDP) family.It can bind to E2F family molecules to form a heterodimeric transcription factor E2F/TFDP complex.The complex is an important regulatory activator of cell cycle, involved in the regulation of cell proliferation, differentiation, apoptosis and other important physiologic